bipolar | CaferMed

Jul 221 min read

Lithium Toxicity is Preventable and Avoidable - Memorize Lithium Interactions

Memorize the factors leading to lithium toxicity, focusing on interactions. PDF of visual mnemonics and 99 versions of this mnemonic song.

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May 122 min read

Arachidonic Acid and Bipolar Disorder

Arachidonic acid (AA), an omega-6 PUFA, may be deficient in bipolar disorder. Bipolar risk is strongly linked to AA-related genes. Lithium ↑

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Aug 27, 20231 min read

Interaction of the week: Lamotrigine (Lamictal) + Valproate (Depakote)

Lamotrigine + Valproate interaction Valproate (divalproex / valproic acid) doubles serum levels of lamotrigine by inHibiting UGT enzymes....

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Mar 19, 20232 min read

The one-page Psychopharmacology Algorithms sheet I refer to on a daily basis

One page PDF, evidence-based medicine reference for psychopharmacology

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Feb 26, 20233 min read

Allopurinol for bipolar mania / The brain on uric acid

New medication mascot for allopurinol, which can be used off-label as adjunctive treatment of bipolar mania

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Feb 12, 20233 min read

Eyeball lithium levels and suicide / Why not 150 mg?

Lower micro-lithium levels appear to be associated with suicide. Why not prescribe lithium 150 mg for prevention of suicide and Alzheimer's

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Feb 5, 20232 min read

Never accelerate lamotrigine titration (and know the UGT interactions)

This post was inspired by the Carlat Podcast: Psychopharm Commandment 4: Lamotrigine Rash. When is it advisable to accelerate the...

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Aug 22, 20202 min read

Virtual Darkness Therapy for Mania

100% blue-light-blocking glasses (amber-tinted) were found highly effective for treatment of acute mania, adjunctively to standard...

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