Jason Cafer MDMay 142 min readInteraction of the week: Fluoxetine (Prozac) + AmitriptylineFluoxetine ↑ amitriptyline x2 and nortriptyline metabolite x9. The danger is arrhythmia. 5-HT toxicity Sx would not be life threatening.
Jason Cafer MDMay 103 min readNitrous Oxide for Treatment-Resistant Depression, Potential Advantages Over (Es)ketamine1-hr of inhaled nitrous oxide is efficacious for depression within 2 hr. NO2 is an NMDA receptor antagonist like (es)ketamine.
Jason Cafer MDMay 93 min readGuide to QT-prolonging medicationAmong the commonly prescribed antipsychotics, 3 have moderate risk of QT prolongation: haloperidol, quetiapine, and ziprasidone (24 mascots)