Memorize Causes of Lithium Toxicity
I wrote a jingle about lithium interactions and AI generated 99 versions of the same song with different genres. See below for the web player, lyrics, and a music video of version #34 showcasing medication mascots and interaction avatars.
This Google Drive folder has mp3 files of all 99 tracks and an updated PDF with lithium interaction visuals (battery chargers, etc).
The top 35 tracks are accessible on Spotify, YouTube Music, and other major platforms.
If you find this useful (or cringeworthy) you can leave a comment on this Reddit post. Thanks for listening!
Video:
Lithium competes with sodium
For renal resorption
Toxic lithium is often defined
As serum level one point five
Lithium competes with sodium
For renal resorption
Toxic lithium is often defined
As serum level one point five
Causes are predictable and avoidable
Watch for interacting meds
Aces, ARBs, thiazides
Loop diuretics, and NSAIDs
Early signs may include
Tremor, nausea, ataxia, fatigue
And possibly altered taste
Aces and ARBs are expected
To increase lithium
By about thirty-six percent
Maybe more
Ace inhibitors are prils
The pril family includes
Lisinopril
Enalapril
Benazepril
Ramipril
Captopril
Quinapril
Fosinopril
Trandolapril
Moexipril
Perindopril
And the most common
And most important to not combine
Is Lisinopril
Trade name Zestril
Lithium competes with sodium
For renal resorption
Toxic lithium is
Predictable and avoidable
Low sodium (hyponatremia) is a culprit
Polydipsia can contribute
Now the angiotensin
Two receptor blockers (ARBs)
Tell me sartan
What’s an ARB?
Tell me sartan
What’s an ARB?
Tell me sartan
What’s an ARB?
ARB
The angiotensin two receptor blockers
Losartan
Valsartan
Irbesartan
Telmisartan
Olmesartan
Candesartan
And azilsartan
Yet another ARB
Also the ARB plus endothelin receptor antagonist
Sparsentan
Lithium competes with sodium
For renal resorption
Toxic lithium is caused
By low sodium (hyponatremia)
Did you know that
Three thousand meters altitude
Quickly elevates serum lithium
Thiazide and thiazide-like diuretics
Are expected to increase lithium
By twenty-five percent
Maybe more
Chlorothiazide
Hydrochlorothiazide
Chlorthalidone
Indapamide
And metolazone
In the zone
In the zone
Lithium competes with sodium
For renal resorption
Toxic lithium is predictable and avoidable
Low sodium (hyponatremia) is a culprit
Rehydrate with electrolytes
NOT free water
Loop diuretics can certainly
Contribute to toxic lithium
Usually in the context
Of older age or hyponatremia
Furosemide
Trade name Lasix
Is a loop
Bumetanide
Is a loop
Torsemide
Is a loop
And ethacrynic acid
Also a loop
Lithium competes with sodium
For renal resorption
Toxic lithium is caused
By low sodium (hyponatremia)
Watch for interacting meds
Aces, ARBs, thiazides
Loop diuretics, and NSAIDs
Plus a couple stand-alones
Cyclosporin
And possibly
Metronidazole (Flagyl)